Recent and Upcoming Activities of ebCTC

2011

5/5/2011
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 4 PM

• Kuna Lecture - Title TBD (G.N. Wogan, MIT)

4/28/2011
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• The B lymphocyte as a cellular target for immunotoxicity by 2,3,7,8-tetrachlorodibenzo-p-dioxin. A tale of mice and men (N. Kaminski, Michigan State U.)

4/14/2011
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Analysis of disease-toxicant interactions in Huntington's Disease and Parkinson's Disease (A. Bowman, Vanderbilt U.)

4/7/2011
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Exposure science and toxicology: collaboration within the 'exposome' framework (P.J. Lioy, EOHSI, UMDNJ)

4/4/2011
Yellin Family Seminar Series, Rutgers Biomedical Engineering Dept. Biomedical Engineering Building Room 102, Rutgers Busch Campus, 1:30 pm

• Morphogenesis of engineered epithelial trees (C. Nelson, Princeton U.)

3/31/2011
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• The use of DNA repair proteins targeted to mitochondria to alter disease (G. Wilson, U. of S. Alabama College of Medicine)

3/28/2011
Yellin Family Seminar Series, Rutgers Biomedical Engineering Dept. Biomedical Engineering Building Room 102, Rutgers Busch Campus, 1:30 pm

• Understanding and overcoming the glial scar: improving regeneration after CNS injury (H. Geller, NIH)

3/24/2011
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Regulation of gene expression by dietary fatty acids (J.P. Vanden Heuvel, Penn State U.)

3/7/2011
Yellin Family Seminar Series, Rutgers Biomedical Engineering Dept. Biomedical Engineering Building Room 102, Rutgers Busch Campus, 1:30 pm

• Biofabrication: Interfacing biology with microfluidics (X. Luo, University of Maryland)

2/28/2011
Yellin Family Seminar Series, Rutgers Biomedical Engineering Dept. Biomedical Engineering Building Room 102, Rutgers Busch Campus, 1:30 pm

• Quantitative ultrasound for imaging tissues: applications to diagnosis & treatment of disease (E. Feleppa, Riverside Research Institute)

2/24/2011
BioMaPS Lecture Series, Hill Center, Room 260, Rutgers Busch Campus, 1:30 PM

• Incomplete DNA methylation and somatic cell memory in human iPS cells" (J. Song, UC San Francisco)

2/21/2011
Genetics Research Seminar, Life Sciences Building Auditorium, 145 Bevier Rd., Busch Campus, 12 PM

• Gene hunting in c. elegans: Exploring nonessential cytoskeletal regulators (S.M. O'Rourke, U. of Oregon)

2/17/2011
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Identifying protein functional sites using in silico mutagenesis (Y. Bromberg, Rutgers U.)

2/16/2011
BioMaPS Lecture Series, Hill Center, Room 260, Rutgers Busch Campus, 1:30 PM

• Imatinib dynamics and cancer vaccines: From agent-based models to PDEs (P. Kim, U. of Utah)

2/10/2011
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• A role for Nuclear Factor-E2 Related Factor 2 (Nrf2) in hypercholesterolemia and lipidemia: Nrf2 goes Rogue (A. Slitt, U. of Rhode Island)

2/7/2011
Yellin Family Seminar Series, Rutgers Biomedical Engineering Dept. Biomedical Engineering Building Room 102, Rutgers Busch Campus, 1:30 pm

• Models for 3‐dimensional cardiovascular tissue constructs (R. Birla, Tulane U.)

2/3/2011
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Safety assessment of omega-3 fatty acids: a nutrigenomic perspective (P. Gillies, Rutgers U.)

1/21/2011
Yellin Family Seminar Series, Rutgers Biomedical Engineering Dept. Biomedical Engineering Building Room 102, Rutgers Busch Campus, 1:30 pm

• The promise of tissue engineering and regenerative medicine for the treatment of catastrophic injuries (J. Kohn, NJ Center for Biomaterials & Rutgers U.)

1/27/2011
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Epigenetics and disease susceptibility (S-M. Ho, University of Cincinatti)

2010

12/10/2010
RWJMS Cancer Pharmacology Program Meeting, RWJMS 4th Floor Conference Room, Piscataway

• Dual active-passive targeting approach for minimizing lung cancer metastases (P. Sinko, Rutgers University)

12/9/2010
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• The how and why of asbestos carcinogenesis (T. Hei, Columbia University Medical Center)

12/6/2010
Yellin Family Seminar Series, Rutgers Biomedical Engineering Dept. Biomedical Engineering Building Room 102, Rutgers Busch Campus, 1:30 pm

• Vascular tissue engineering: Controlling vascular smooth muscle cell phenotype (J. Wong, Boston University)

12/5-8/2010
Society of Risk Analysis Annual Meeting, Salt Lake City, UT

• A whole-body physiologically-based pharmacokinetic model of tocopherol for rats to support its studies as a protective agent against neurotoxicants (D.P. Mukherjee, P.G. Georgopoulos, S.S. Isukapalli) [abstract]

12/2/2010
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Drug efflux transporters at the blood-brain barrier as dioxin targets (David Miller, NIEHS/NIH)

11/18/2010
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Genetical genomics of lung growth, injury and remodeling (George Leikauf, University of Pittsburgh)

11/17/2010
BioMaPS Lecture Series, Hill Center, Room 260, Rutgers Busch Campus, 1:30 PM

• Why are chemotaxis receptors clustered but other receptors aren't? (N. Wingreen, Princeton University)

11/15/2010
Yellin Family Seminar Series, Rutgers Biomedical Engineering Dept. Biomedical Engineering Building Room 102, Rutgers Busch Campus, 1:30 pm

• Unlocking multiscale mechanical interactions in engineered tissues (E. Sander, University of Minnesota)

11/15-16/2010
NIEHS Centers for Nanotechnology Health Implications Research (NCNHIR) Consortium Meeting, Research Triangle Park, NC

• A modeling system for assessing risk from engineered nanomaterials (ENMs) (A.F. Sasso, P. Shade, C.J. Brinkerhoff, S.S. Isukapalli, P.G. Georgopoulos)

11/11/2010
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Hurricane Katrina and its moldy aftermath to "sick building syndrome" and its elusive etiology (Joan Bennett, Rutgers University)

11/10/2010
BioMaPS Lecture Series, Hill Center, Room 260, Rutgers Busch Campus, 1:30 PM

• The cell's compass: A local-excitation, global-inhibition biased excitable network controls temporal and spatial responses to chemoattractants (P. Iglesias, Johns Hopkins)

11/4/2010
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Acetaminophen and the cardiovascular system (Gary Merrill, Rutgers University)

11/3/2010
Yellin Family Seminar Series, Rutgers Biomedical Engineering Dept. Biomedical Engineering Building Room 102, Rutgers Busch Campus, 1:30 pm

• Protein engineering for biosensors and biofuel cells (S. Banta, Columbia University)

10/28/2010
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Vesicular storage of monoamines in Parkinson’s Disease (Gary Miller, Emory University)

10/25/2010
Yellin Family Seminar Series, Rutgers Biomedical Engineering Dept. Biomedical Engineering Building Room 102, Rutgers Busch Campus, 1:30 pm

• Cancer drug delivery to solid tumors: Barriers and solutions for enhanced efficacy (J. Cini, Biopharm Protein Consulting Group)

10/20/2010
BioMaPS Lecture Series, Hill Center, Room 260, Rutgers Busch Campus, 1:30 PM

• Cultivated and wild: Using genomics to understand plastid endosymbiosis (D. Bhattacharya,Rutgers University)

10/11/2010
Yellin Family Seminar Series, Rutgers Biomedical Engineering Dept. Biomedical Engineering Building Room 102, Rutgers Busch Campus, 1:30 pm

• Disruptive innovations in personalized medicine (A. Singh, Bioimagene)

10/6/2010
BioMaPS Lecture Series, Hill Center, Room 260, Rutgers Busch Campus, 1:30 PM

• Predicting protein-ligand binding affinities from molecular simulations (D. Mobley, University of New Orleans)

10/6/2010
Yellin Family Seminar Series, Rutgers Biomedical Engineering Dept. Biomedical Engineering Building Room 102, Rutgers Busch Campus, 1:30 pm

• Cellular processing of responsive drug and gene delivery biomaterials (M. Sullivan, U. Delaware)

9/30/2010
BioMaPS Lecture Series, Hill Center, Room 260, Rutgers Busch Campus, 12:30 PM

• In silico analysis of sequence dependent structural features of promoter regions in genomic DNA (M. Bansal, Indian Institute of Science)

9/30/2010
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Visualizing neurotoxicity and pathophysiology in vivo: Effects of heavy metal exposure in a transgenic mouse model (John McGann, Rutgers University)

9/22/2010
USEPA STAR Progress Review Meeting, Research Triangle Park, NC

• A multiscale modeling system for co-occurring bioaerosols and photochemical air pollutants to support studies of population exposure under climatic change scenarios (C. Efstathiou, S. Isukapalli, L.J. Bielory, P.G. Georgopoulos)

9/20/2010
Yellin Family Seminar Series, Rutgers Biomedical Engineering Dept. Biomedical Engineering Building Room 102, Rutgers Busch Campus, 1:30 pm

• Molecular signaling in stem cell-derived vascular networks (S. Li, UMDNJ-RWJMS)

9/16/2010
BioMaPS Lecture Series, Hill Center, Room 260, Rutgers Busch Campus, 1:30 PM

• Towards a mechanistic understanding of inflammation and physiologic variability: A translational physiomics approach (I. Androulakis, Rutgers University)

9/16/2010
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Role of the FRY tumor suppressor gene and circadian gene expression in tumor progression and chemoprevention (H. Zarbl, UMDNJ-RWJMS)

9/13/2010
Yellin Family Seminar Series, Rutgers Biomedical Engineering Dept. Biomedical Engineering Building Room 102, Rutgers Busch Campus, 1:30 pm

• Stem cells and cancer (J. Glod, CINJ)

6/16/2010
CounterACT Center Seminar, UMDNJ-CINJ Auditorium, New Brunswick, NJ, 4 PM

• Mitochondria and apoptosis: New roads to ruin (D.R. Green, St. Jude Children's Research Hospital)

5/31-6/3/2010
10th International Conference on Bioinformatics and Bioengineering (BIBE-2010), Philadelphia, PA. Pesentation by ebCTC researchers:

• Effects of triadimefon on the metabolism of cultured hepatocytes (V.V. Iyer, I.P. Androulakis, C.M. Roth, M.G. Ierapetritou)

5/20/2010
EOHSI Seminar Series Kuna Lecture, EOHSI Room A-B, Rutgers Busch Campus, 12 PM

• Metabonomics - Applications in Toxicology (D. Robertson, Bristol-Meyers Squibb)

5/11/2010
CABM Seminar, CABM Room 010, Rutgers Busch Campus, 12:00 PM

• Stops and starts in early neocortical development (Joseph LoTurco, University of Connecticut)

5/6/2010
EOHSI/NIEHS Seminar Series Kuna Lecture, EOHSI Room C, Rutgers Busch Campus, 4 PM

• Alternaterations of xenobiotic biotransformation by sulforaphane: from molecular mechanism to clinical trial (David Eaton, University of Washington)

5/3/2010
Yellin Family Seminar Series, Rutgers Biomedical Engineering Dept. Biomedical Engineering Building Room 102, Rutgers Busch Campus, 1:30 pm

• Unraveling functional mechanisms of protein machineries by NMR (Babis Kalodimos, Rutgers University)

5/3/2010
Rutgers Department of Genetics Seminar Series, Life Sciences Building Auditorium, Rutgers Busch Campus, 12 PM

• Stress resistance, insulin-like signaling, and aging in C. elegans (Keith Blackwell, Harvard University)

4/30/2010
Bioinformatics and Computational Toxicology Seminar Series, EOHSI Room 402, Rutgers Busch Campus, 2 PM

• Sensitivity studies of contaminant dispersion and exposure in urban environments using Computational Fluid Dynamics (CFD) simulations (Sagnik Mazumdar, EOHSI)

4/29/2010
Bioinformatics and Computational Toxicology Seminar Series, EOHSI Room 402, Rutgers Busch Campus, 3 PM

• Agent-based modeling (ABM) with geographic information system (GIS) for axon guidance in Caenorhabditis Elegans (C. Elegans)
  (Christopher Yung, CCL, EOHSI)

4/29/2010
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Therapy-related myeloid leukemia - a model for environmental cancer (Richard Larson, University of Chicago)

4/27/2010
Bioinformatics and Computational Toxicology Seminar Series, EOHSI Room 402, Rutgers Busch Campus, 3PM

• A multiscale model for the assessment of autonomic dysfunction in human endotoxemia (Pegy Foteinou, Rutgers Department of Biomedical Engineering and ebCTC)

4/26/2010
Yellin Family Seminar Series, Rutgers Biomedical Engineering Dept. Biomedical Engineering Building Room 102, Rutgers Busch Campus, 1:30 pm

• Systematic analysis of BMP signaling in evolving tissues (Nir Yakoby, Rutgers U.)

4/22/2010
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Linking air quality, transportation and health impacts (Michael Brauer, University of British Columbia)

4/20/2010
Invited Seminar at USFDA Center for Food Safety and Applied Nutrition, College Park, MD

• A multiscale integrated model-based approach for the analysis of exposure and health risks (P.G. Georgopoulos)

4/20/2010
Introductory Software Training Series, EOHSI Room 402, Rutgers Busch Campus, 3 PM

• Capabilities of Arraytrack - a bioinformatics resource for DNA microarray and systems biology (Jocelyn Alexander, EOHSI)

4/16/2010
Bioinformatics and Computational Toxicology Seminar Series, EOHSI Room 402, Rutgers Busch Campus, 1PM

• Computational Fluid Dynamics (CFD) simulation of pyrethrin transport and deposition in an aircraft cabin (Marko Milanez, EOHSI)

4/15/2010
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Nanoparticle inhalation alters skeletal muscle and coronary microvascular reactivity (Timothy Nurkiewicz, West Virginia University)

4/15/2010
Introductory Software Training Series, EOHSI Room 304, Rutgers Busch Campus, 3 PM

• Simulink capabilities with application to physiologically based pharmacokinetic (PBPK) modeling (Alan Sasso, EOHSI)

4/13/2010
PhD Thesis Defense, Biomedical Engineering Building, Rutgers Busch Campus, 3:30 PM

• A multiscale model for the assessment of autonomic dysfunction in human endotoxemia (ebCTC researcher Panagiota (Pegy) Foteinou; Thesis Advisor: Professor Ioannis Androulakis)

4/8/2010
Introductory Software Training Series, EOHSI Room 402, Rutgers Busch Campus, 3 PM

• Accessing and using the environmental bioinformatics Knowledge Base (ebKB) (Sastry Isukapalli and Jocelyn Alexander, EOHSI)

4/8/2010
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Human behavioral neurotoxicology: established methods and evidence from research on organophosphorus pesticides (W. Kent Anger, Oregon Health and Science University)

4/6-7/2010
Exposure-Based Chemical Prioritization Workshop: Exploring Opportunities for Collaboration, USEPA, Research Triangle Park, NC (Participation by ebCTC researcher, Sastry Isukapalli)

4/1/2010
Introductory Software Training Series, EOHSI Room 402, Rutgers Busch Campus, 3 PM

• Systems Biology Graphical Notation (SBGN) with toxicological applications (C.J. Brinkerhoff, EOHSI)

3/30/2010
Introductory Software Training Series, EOHSI Room 402, Rutgers Busch Campus, 3 PM

• Ingenuity Pathway Analysis (IPA) application to environmental chemical exposures: Conazoles and pthalates (Meric Ovacik, ebCTC and RU Biomedical Engineering)

3/23/2010
Introductory Software Training Series, EOHSI Room 402, Rutgers Busch Campus, 3 PM

• Exposure Related Dose-Estimating Model (ERDEM) capabilities with case studies (Jocelyn Alexander, EOHSI)

3/19/2010
Bioinformatics and Computational Toxicology Seminar Series, EOHSI Room 402, Rutgers Busch Campus, 1 PM

• An integrated toxicokinetic-toxicodynamic (TK/TD) model for arsenic in hepatocytes (Spyros Stamatelos, EOHSI)

3/18/2010
Introductory Software Training Series, EOHSI Room A, Rutgers Busch Campus, 3 PM

• ArcGIS capabilities for environmental health applications with examples from the National Children's Study (Christopher Yung, EOHSI)

3/18/2010
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Microglia and manganese neurotoxicity (Bin Liu, University of Florida)

3/16/2010
Introductory Software Training Series, EOHSI Room 304, Rutgers Busch Campus, 2 PM

• Managing references with Endnote, BibTex, and other tools
  (Linda Everett, EOHSI)

3/12/2010
Introductory Software Training Series, EOHSI Room 402, Rutgers Busch Campus, 3 PM

• CompuCell 3D capabilities with case studies in systems toxicology (Dwaipayan Mukherjee, EOHSI)

3/9/2010
EOHSI/Clinical Research and Occupational Medicine Seminar, EOHSI Room A-B, Rutgers Busch Campus, 1:30 PM

• A real-world study of health effects of exposure to diesel exhaust (Jim Zhang, UMDNJ School of Public Health)

3/5/2010
Bioinformatics and Computational Toxicology Seminar Series, EOHSI Room 402, Rutgers Busch Campus, 1 PM

• Physiologically based toxicokinetic and toxicodynamic model for oxidative stress following exposures to trichloroethylene (C.J. Brinkerhoff, EOHSI)

3/4/2010
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Molecular clocks and circadian modulation of stress reponse (Marina Antoch, Rosewell Park Cancer Institute)

2/19/2010
Bioinformatics and Computational Toxicology Seminar Series, EOHSI Room 402, Rutgers Busch Campus, 2 PM

• PBPK modeling of alpha-tocopherol distribution in rats (Dwaipayan Mukherje, EOHSI)

2/18/2010
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Methylmercury-induced disruption of intraneuronal divalent cation homeostasis: cell-type dependence and sites of action (William Atchison, Michigan State University)

1/28/2010
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Type XV collagen: features and proposed functions of novel collagen/proteoglycan (Peter Amenta, UMDNJ-Robert Wood Johnson Medical School)

1/22/2010
Bioinformatics and Computational Toxicology Seminar Series, EOHSI Room 402, Rutgers Busch Campus, 12 PM

• Developmental pesticide exposure: A new risk factor for ADHD (Jason Richardson, EOHSI)

2009

12/3/2009
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• The role of pharmacokinetic modeling in toxicity testing (Michael DeVito, USEPA)

12/1/2009
DNA Microarray Workshop, EOHSI Room 402, Rutgers Busch Campus, 12 PM

• Fundamentals in the use of DNA Microarrays and pathway analysis: Experimental design, potentials, and limitations (G. Rajagopal, G. Schemman, G. Miles - CINJ)

11/12/2009
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Estrogen and breast cancer (Jose Russo, Fox Chase Cancert Center)

11/8-13/2009
Annual Meeting of American Institute of Chemical Engineers, Nashville, TN. Presentations by ebCTC researchers:

• Understanding mechanisms of conazole toxicity in cultured hepatocytes (V.V. Iyer, M.G. Ierapetritou, C.M. Roth)
• A multi-scale model for the assessment of autonomic dysfunction in human endotoxemia (P.T. Foteinou, S.E. Calvano, S.F. Lowry, I.P. Androulakis)
• Agent-based imulation of endotoxin induced acute inflammatory response in human blood leukocytes (X. Dong, P.T. Foteinou, S.E. Calvano, S.F. Lowry, I.P. Androulakis)
• Species comparison analysis based on pathways (M. Ovacik, I.P. Androulakis)
• Analysis of amino acids supplementation in hepatocyte culture using optimization modeling (H. Yang, C.M. Roth, M.G. Ierapetritou)
• Optimization based pathway analysis to elucidate the effects of burn injury on the hepatic metabolism (M.A. Orman, F. Berthiaume, I.P. Androulakis, M.G. Ierapetritou)

11/5/2009
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Environmental arsenic signals for pathogenic vascular remodeling (Aaron Barchowsky, University of Pittsburgh)

11/1-5/2009
2009 Annual Conference of ISES, Minneapolis, MN (ebCTC researcher Sastry Isukapalli is chairing a symposium "Integrative Exposure Biology and Computational Toxicology for Risk Assessment") Presentations by ebCTC researchers:

• Linking exposure dynamics with health effects through biological modeling: Case study with TCE exposure and oxidative stress (C.J. Brinkerhoff, P.G. Georgopoulos) [abstract]
• Integrative source-to-dose-to-effect modeling for interpreting biomonitoring data in an exposure context (P.G. Georgopoulos, S.S. Isukapalli) [abstract]
• Multiscale mechanistic models in exposure assessment: Case studies with virtual organs (S.S. Isukapalli) [abstract]
• Pathway modeling of microarray data of the rat testes after in utero DBP exposure (M. Ovacik, M.G. Ierapetritou, P. Georgopoulos, W. Welsh, S. Euling, B. Sen, K. Gaido, I.P. Androulakis) [abstract]
• Integrated computational models for supporting risk assessment: case studies with chemical mixtures (A.F. Sasso, K. Krishnan, S.S. Isukapalli) [abstract]
• Biological spectra profile analysis in computational toxicology: Linking the bioactivities and molecular structures of chemical datasets (W.J. Welsh) [abstract]

10/28-30/2009
4th International Conference on Oxidative/Nitrosative Stress and Disease, New York Academy of Science (NYAS), New York, NY. Presentations by ebCTC researchers:

• Integrative modeling of chemically induced oxidative stress: A case study with trichloroethylene (C.J. Brinkerhoff, S.S. Isukapalli, P.G. Georgopoulos)

10/22/2009
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Type XV collagen: features and proposed functions of novel collagen/proteoglycan (Peter Amenta, UMDNJ-RWJMS)

10/8/2009
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Visual effects of organic solvents: acute, chronic and extrapolation modeling (William K. Boyes, USEPA)

10/1/2009
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Metabolic basis of perfluoroalkyl acid toxicity (Kenneth Wallace, University of Minnesota Medical School)

10/7-10/2009
Biomedical Engineering Society Annual Meeting, Pittsburgh, PA. Presentations by ebCTC researchers:

• A multiscale model for the assessment of autonomic dysfunction in human endotoxemia (P.T. Foteinou, S.E.Calvano, S.F. Lowry, I.P. Androulakis)
• Agent-based simulation of endotoxin induced acute inflammatory response in human blood leukocytes (X. Dong, P.T. Foteinou, S.E. Calvano, S.F. Lowry, I.P. Androulakis)

10/1/2009
Computational Toxicology Centers Science to achieve Results (STAR) Progress Review Workshop USEPA Main Campus, Research Triangle Park, NC. Scientists from EPA's STAR Computational Toxicology and Bioinformatics Centers will present their research findings to date and future endeavors.

• Environmental Bioinformatics and Computational Toxicology Center (ebCTC): Research in multiscale modeling of the effects of environmental toxicants (W.J. Welsh, P.G. Georgopoulos)

9/29-30/2009
USEPA Board of Scientific Counselors Computational Toxicology Review. USEPA Main Campus, Research Triangle Park, NC. Presentations by ebCTC researchers:

• Environmental Bioinformatics and Computational Toxicology Center (ebCTC): Research collaborations with USEPA in multiscale modeling of the effects of environmental toxicants (W.J. Welsh, P.G. Georgopoulos)

9/24/2009
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• All particles, great and small (Lung Chi Chen, NYU School of Medicine)

9/20-23/2009
5th International Conference on Toxicogenomics (ICT)
and 2nd Toxicogenomics Integrated Environmental Science (TIES), Seoul, Korea (ebCTC researcher Weida Tong is chairing a session on "MicroArray Quality Control")

9/2-6/2009
31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2009), Minneapolis, MN (ebCTC researcher Ioannis Androulakis is co-chairing a session on"Advances in Theory and Clinical Applications of Biological Network Studies") Presentations by ebCTC researchers:

• A unified multiscale field/network/agent based modeling framework for human and ecological health risk analysis (P.G. Georgopoulos, S. Isukapalli)
• Nonlinear bionetwork structure inference using the random sampling-high dimensional model representation (RS-HDMR) algorithm (M. Miller, X. Feng, G. Li, H. Rabitz)

8/30-9/4/2009
10th Annual Conference on Systems Biology (ICSB 2009), Stanford, CA. Presentation by ebCTC researchers:

• An integrated mathematical model for studying toxicokinetic and toxicodynamic processes following exposures of human hepatocytes to arsenic compounds (S.K. Stamatelos, C.J. Brinkerhoff, S.S. Isukapalli, P.G. Georgopoulos) [abstract]

8/28-30/2009
8th International Conference on Complexity in Acute Illness (ICCAI), Palo Alto, CA. Presentation by ebCTC researchers:

• A Multiscale model for the assessment of autonomic dysfunction in human endotoxemia (P.T. Foteinou, S.E. Calvano, S.F. Lowry, I.P. Androulakis)

6/6-11/2009
7th International Conference on Pathways, Networks, and Systems Medicine, Corfu, Greece. Presentation by ebCTC researchers:

• Analysis of liver cell metabolism after burn injury (M.A. Orman, F. Berthiaume, I. Androulakis, M. Ierapetritou)

5/20/2009
3rd Annual SYSTEMS TOXICOLOGY SYMPOSIUM
presented by ebCTC at EOHSI, Piscataway, NJ.
Free and open to the research community

5/14-15/2009
First ToxCast Data Analysis Summit (TDAS), USEPA Campus, Research Triangle Park, NC (ebCTC researchers Weida Tong and William Welsh are among the organizing committee). Presentations by ebCTC researchers:

Presentations

• Biological profile analysis of the ToxCast chemicals: Linking biological activity profiles to molecular structure (W.J. Welsh)
• Predicting in vivo toxicities using optimal methods for re-ordering and machine learning (P.A. DiMaggio, C.A. Floudas*, J.D. Rabinowitz, H.A. Rabitz) *presenter
• Prediction of liver toxicity in the animal study using the mechanistically relevant in vitro screening assay data – Lessens learned from the EPA ToxCast project (Z. Su, H. Hong, W. Tong*) *presenter

Posters

• Data needs for progressing from hazard characterization to risk assessment: Analysis focusing on chemicals from the ToxCast database (C.J. Brinkerhoff, J.A. Alexander, C.T. Yung, S.S. Isukapalli, P.G. Georgopoulos)
• Exposure reconstruction from biomonitoring data using screening level approaches: application to chemicals in the ToxCast database (C.J. Brinkerhoff, J.A. Alexander, A.F. Sasso, S.S. Isukapalli, P.G. Georgopoulos)
• Progress in the development of ebTrack, an open environmental bioinformatics system: design considerations related to the support of consistent multi-attribute ToxCast data analyses (P.G. Georgopoulos, M. Chen, S.S. Isukapalli, W. Welsh, W. Tong)
• Relating toxicity profiles to molecular structures: A preliminary analysis of the transcription factor assays data from Attagene Inc. (D. Chekmarev, V. Kholodovych, N. Ai, P.G. Georgopoulos, W. Tong, W.J. Welsh)

5/11-13/2009
Toxicity Pathway Based Risk Assessment: Preparing for Paradigm Change. The National Academy of Sciences, Washington, DC. Presentations by ebCTC researchers:

• Application of an integrated bioinformatics system for pathway-based analysis of toxicity data (S. Isukapalli, D. Gerecke, Y.C.  Chang, M. Chen, I. Androulakis, W. Welsh, W. Tong, P.G. Georgopoulos)
• Dissecting enzyme regulation by multiple allosteric effectors using the random sampling – high dimensional model representation algorithm (J. Rabinowitz, J. Hsiao, K. Gryncel, E. Kantrowitz, X. Feng, G.Li, H. Rabitz)
• Metabolic flux analysis: Understanding mechanisms of conazole toxicity in cultured hepatocytes (V. Iyer, I. Androulakis , C.M. Roth, M.G. Ierapetritou)
• Toxicity pathway modeling of chemically induced oxidative stress: A case study with trichloroethylene (C.J. Brinkerhoff, S.S. Isukapalli, P.G. Georgopoulos)

5/6/2009
EOHSI/NIEHS Seminar Series (Kuna Lecture), EOHSI Room C, Rutgers Busch Campus, 4 PM

• Complex responses to DNA damaging agents (Leona Samson, MIT Center for Environmental Health Sciences)

5/5/2009
Exposure Science Community of Practice Teleconference. USEPA Campus, RTP, NC, 11 AM

• Connecting environment, biology, and behavior for human exposure and risk assessment: Integrative modeling approaches (P.G. Georgopoulos)

4/30/2009
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Halting the progression of neurodegenerative diseases: What does Nrf2 have to do with it? (Jeffery Johnson, University of Wisconsin)

4/23/2009
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Impaired coronary artery function following short-term diesel exhaust inhalation (Nancy Kanagy, University of New Mexico)

4/21-23/2009
v-Tissue 2009: The EU-US Workshop on Virtual Tissues. USEPA, Research Triangle Park, NC. Presentation by ebCTC researcher:

• Frameworks for linking exposure, dosimetry and toxicity (P.G. Georgopoulos)

3/26/2009
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Mechanisms and prevention of tobacco-induced cancer: Recent studies (Stephen Hecht, University of Minnesota)

3/20/2009
ebCTC Science Day, EOHSI Room 402, Rutgers Busch Campus, 12 PM

• Role of autophagy in mammary tumorigenesis (Vassiliki Karantza-Wadsworth, UMDNJ-RWJMS and Cancer Institute of NJ)

3/18/2009
Cancer Institute of NJ, Genetic Epidemiology and Population Biology Research Program Meeting, Institute for Advanced Studies, Princeton, NJ

• Environmental carcinogens and exposure biology challenges (P.G. Georgopoulos)

3/15-19/2009
48th Annual Meeting of the Society of Toxicology (SOT), Baltimore, MD. Presentations by ebCTC researchers:

• A novel algorithm for computing interaction-based hazard index for the health risk assessment of chemical mixtures (S.S. Isukapalli, A.F. Sasso, P.G. Georgopoulos, K. Krishnan) [abstract]
• An integrated species comparison analysis based on biological pathways (M. Ovacik, S. Euling, B. Sen, P.G. Georgopoulos, M.G. Ierapetritou, I.P. Androulakis) [abstract]
• Temporal pathway activity analysis of transcriptional profiling of in utero exposure to d-n-butyl phthalate (M. Ovacik, M.G. Ierapetritou, P.G. Georgopoulos, W. Welsh, S. Euling, B. Sen, K. Gaido, I.P. Androulakis) [abstract]

3/13-17/2009
Annual Meeting of the American Academy of Allergy, Asthma, and Immunology, Washington, DC. Presentation by ebCTC researchers:

• A modeling system for supporting population exposure assessment to bioaerosols and other air pollutants (S.S. Isukapalli, C. Efstathiou, L.J. Bielory, P.G. Georgopoulos) [abstract]

3/6/2009
ebCTC Science Day, EOHSI Room 402, Rutgers Busch Campus, 12 PM

• Discovery of novel microRNA-encoding genes in human embryonic stem cells by SOLiD deep sequencing (Ronald Hart, W.M. Keck Center for Collaborative Neuroscience)

3/5/2009
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Epigenetic mechanisms of metal carcinogenesis (Max Costa, NYU School of Medicine)

3/4/2009
Rutgers Department of Pharmacy Seminar, Ernest Mario School of Pharmacy, Room 111, Rutgers Busch Campus, 12 PM

• Elucidating the 'Jekyll and Hyde' nature of PXR: The case for discovering antagonists (Sean Ekins, Collaborative Drug Discovery, Inc. and ebCTC)

2/26/2009
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Human pulmonary and cardiovascular effects of very small particles (Mark Frampton, University of Rochester)

2/19/2009
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Human fetal testis xenotransplants and endocrine disruptions (Kim Boekelheide, Brown University)

2/5/2009
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Endocrine disruption within the HPG axis by bisphenol-a and soy (Heather Patisaul, North Carolina State University)

1/18-21/2008
Second International Conference on Biomolecular Engineering, Santa Barbara, CA. Presentation by ebCTC researchers:

• Multiscale physiologically based toxicokinetic (PBTK) modeling: A case study for arsenic compounds (S.K. Stamatelos, C.J. Brinkerhoff, A.F. Sasso, S.S. Isukapalli, P.G. Georgopoulos) [abstract]
• Approaches towards a reversed engineered model of systemic inflammation in humans (P.T. Foteinou, S.E. Calvano, S.F. Lowry, I.P. Androulakis) [abstract]

2/13/2009
Biostatistics Seminar, UMDNJ School of Public Health Room 3A/3B, Busch Campus, 3:00 PM

• Addressing heterogeneity in the analysis of clinical genomics studies (John Storey, Princeton University)

1/13/2009
EOHSI Seminar, EOHSI Room A-B, Rutgers Busch Campus, 1:30 PM

• Urban residential pyrethroid insecticide use during pregnancy and effects on infant neurodevelopment (Megan K. Williams, Columbia University)

1/13/2009
CABM Seminar, CABM Room 010, Rutgers Busch Campus, 12:00 PM

• Growth control by fat in flies and mice (Helen McNeill, University of Toronto)

2008

12/15/2008
UMDNJ-RWJMS Seminar, RWJMS, Rutgers Busch Campus, Room V10, 4 PM

• Transcriptional corepressors in development and diseases (Chih-Cheng Tsai, UMDNJ-RWJMS)

12/15/2008
Human Genetics Institute Seminar, Life Sciences Bldg. Auditorium, Rutgers Busch Campus, 12 pm

• Understanding inherited genetic susceptibility to cancer (Robert Klein, Memorial Sloan Kettering Cancer Center)

12/12/2008
Cell Biology and Neuroscience Seminar, Nelson Room B228, Rutgers Busch Campus, 12 PM

• Regulating nicotinic synapses in the nervous system (Joseph Margiotta, University of Toledo Medical Center)

12/11/2008
UMDNJ Seminar, UMDNJ Tower, V10, Busch Campus, 4:00 pm

• Design of Tunable Proteins via Phosphorylation, Electronics and Stereoelectronic Effects (Neal Zondlo, University of Delaware)

12/08/2008
CABM Seminar, CABM 010, Rutgers Busch Campus, 12:00 pm

• The NIH Protein Structure Initiative: Achievements and Visions for the Future (Gaetano Montelione, Rutgers University)

12/7-10/2008
Society of Risk Analysis (SRA) 2008 Annual Meeting, Boston, MA. Presentation by ebCTC researchers:

• A novel interaction-based algorithm for predicting biological doses during chronic exposures to chemical mixtures (S.S. Isukapalli, A.F. Sasso, P.G. Georgopoulos, K. Krishnan) [abstract]

12/5/2008
NJ Universities Homeland Security Research Consortium, Princeton, NJ. Presentation by ebCTC researchers:

• Computational modeling for supporting emergency event response: population exposures to anthrax (S.S. Isukapalli, P.J. Lioy, P.G. Georgopoulos) [abstract]
• Bioinformatics techniques for disease detection and finding medical countermeasures: Case study with sulfur mustard (D.R. Gerecke, M. Chen, S.S. Isukapalli, M.K. Gordon, Y.C. Chang. W. Tong, I.P. Androulakis, P.G. Georgopoulos) [abstract]

11/26/2008
ChemBioE Seminar, BME Room 122, Rutgers Busch Campus, 10:20 am

• Molecular systems biology: Building bridges through multiscale modeling and high-performance computing (R. Radhakrishnan)

11/25/2008
EOHSI Seminar, EOHSI A&B, Rutgers Busch Campus, 1:30 pm

• Environmental Carcinogenesis (Michael Gallo, EOHSI)

11/16-21/2008
2008 AIChE Annual Meeting, Philadelphia, PA. Presentations by ebCTC researchers:

• Physiologically-based inhalation dosimetry modeling for nanoparticles: Considerations of activity, age, and gender [abstract]
• In silico modeling of uptake and metabolism of arsenicals in hepatocytes with implications for hepatotoxicity [abstract]
• Indirect response model of arsenic exposure on gene expression [abstract]
• Effects of glucose and insulin levels on HepG2 cell metabolism [abstract]
• Effects of hormone and amino acid supplementation in optimal liver specific functions of hepatocytes [abstract]
• De novo protein design of complement 5a [abstract]
• A novel mixed-integer linear optimization framework for the identification of post-translationally modified proteins using ETD/ECD tandem mass spectrometry [abstract]
• De novo protein design based on binding affinity predictions for the discovery of novel inhibitors for Complement 3 and HIV-1 [abstract]
• De novo identification of biomarker proteins using tandem mass spectrometry [abstract]
• A novel approach for residue contact prediction in beta and alpha/beta proteins [abstract]
• Single sequence secondary structure prediction for globular proteins [abstract]

11/6/2008
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Differential regulation of the notch-hes1-mash1 signaling pathway during gestational lead exposure selectively increases the number of late-born retinal neurons, but not Muller Glial cells (Donald Fox, University of Houston)

10/29/2008
ChemBioE Seminar, BME Room 122, Rutgers Busch Campus, 10:20 AM

• Elucidating the control mechanism for DNA damage repair with the p53-Mdm2 system: single cell data analysis and ensemble modeling (B. Ogunnaike)

10/23/2008
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Scavenger receptors in regulating lung inflammation (Andrij Holian, University of Montana)

10/22/2008
Cancer Institute Seminar, The Cancer Institute of New Jersey, Auditorium A, 4:00 PM

• How the Genome and the Computer are Changing Biomedical Science (David Botstein, Lewis-Sigler Institute for Integrative Genomics)

10/15/2008
ChemBioE Seminar, BME Room 122, Rutgers Busch Campus, 10:20 AM

• Dynamic flux balance models for genome-scale analysis and optimization of yeast metabolism (M. Henson)

10/12-16/2008
ISEE/ISEA 2008 Conference, Pasadena, CA. Presentation by ebCTC researchers:

• Model estimates of arsenic exposure and dose and evaluation with 2003 NHANES data (J. Xue, V. Zartarian, S.W. Wang, P.G. Georgopoulos) [abstract]

10/8/2008
BioMaPS Lecture Series, Fiber Optics Auditorium, Rutgers Busch Campus, 4 PM

• On Inverse Problems in Biology (S. Liebler, Rockefeller University)

10/3/2008
ebCTC Science Day at EOHSI. Presentations and discussions on "Computational toxicology studies on interactions of the hepatic nuclear receptor PXR with xenobiotics" led by Drs. Sean Ekins and William Welsh

10/1/2008
BioMaPS Lecture Series, Hill Center, Room 260, Rutgers Busch Campus, 1:30 PM

• Decoding the regulatory genome and proteome (O. Elemento, Princeton University)

9/24/2008
Gould Lecture Series in Molecular and Cellular Medicine, Child Health Institute of New Jersey, Room 3101, 89 French Street, New Brunswick

• Control of Stem Cells (Stuart H. Orkin, MD, Harvard Medical School)

9/22/2008
PhD Thesis Defense, Room 122 of the Biomedical Engineering Building at Rutgers Busch Campus, 2 PM

• A Systems Biology Approach for Assessing Corticosteroid Activity(ebCTC researcher Eric Yang; Thesis Advisor: Professor Ioannis Androulakis)
  

9/18/2008
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• Cerebellar Granule Neuron Precursors are Targets for Dioxin Exposure: Does the Aryl Hydrocarbon Receptor Play a Role in Neurogenesis? (L. Opanashuk, Univ. of Rochester Medical School)

9/15/2008
BioMaPS Lecture Series, Biomedical Engineering, Room 102, Rutgers Busch Campus, 1:30 PM

• Computational systems bioengineering: From molecules to networks to cells (J. Liang, University of Illinois-Chicago)

9/11/2008
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus, 12 PM

• The role of age and gender in the genetic susceptibility to inhaled pollutants - animal models (T. Gordon, NYU School of Medicine)

9/10/2008
BioMaPS Lecture Series, Center for Advanced Biotechnology & Medicine, Rutgers Busch Campus, Room 010, 12 PM

• Structural Studies of Neurotrophic Factors and Their Ligands (A Goldman, University of Helsinki)

9/3/2008
BioMaPS Lecture Series, Hill Center, Room 260, Rutgers Busch Campus, 1:30 PM

• Molecular Characteristics of Renal Cell Carcinoma Contributing to Response to Targeted Therapy (W. Kimryn Rathmell - University of North Carolina)

6/29-7/3/2008
Protection and Restoration of the Environment IX (PRE9) Conference, Kefalonia, Greece. Presentations by ebCTC researcher:

• Mechanistic studies of environmental causes of human disease: a bionetwork dynamics modeling approach (P.G. Georgopoulos) [abstract]

5/14/2008
CABM Seminar, Center for Advanced Biotechnology and Medicine, Rutgers Busch Campus, Room 01, 12:00 PM0

• Mechanisms of post-transcriptional gene control (J. Manley, Columbia University)

5/7/2008
Miller Distinguished Lecture, Ernest Mario School of Pharmacy, Rutgers Busch Campus

• Mechanism of action of non-genotoxic hepatocarcinogens (Frank J. Gonzalez of NIH)

4/30-5/1/2008
2nd Annual SYSTEMS TOXICOLOGY SYMPOSIUM:
Multiscale Modeling, from Molecules to Organisms
A symposium presented by ebCTC at EOHSI, Piscataway, NJ. Free and open to the research community - over 100 attendees registered.

4/25/2008
Ernest Mario School of Pharmacy Seminar, Rutgers Busch Campus, Piscataway, NJ.

• Interactions between the aryl hydrocarbon receptor (AhR) and Ras/Raf signaling pathways in human melanoma cells (Lori White, Rutgers University)

4/14-17/2008
International Conference on Health Sciences Simulation, Ottawa, Canada. Presentation by ebCTC reserchers:

• A physiologically-based algorithm for predicting internal dose of inhaled toluene: applications for high dose to low dose and rodent to human extrapolations (S.S. Isukapalli, K. Price, P.G. Georgopoulos, K. Krishnan) [abstract]

3/18/2008
SOT Annual Meeting & ToxExpo 2008, Seattle, WA. Presentation by ebCTC reserchers:

• Toxicogenomic studies reveal the transsulfuration pathway as a possible mechanism for liver toxicity (M. Chen, L.K. Schnackenberg, R. Holland, R.D. Beger, Q. Shi, S. Isukapalli, P.G. Georgopoulos, W. Welsh, W. Tong) [presentation]

3/12/2008
*Computational Toxicology Seminar, USEPA, Research Triangle Park, NC. Presentation by ebCTC resercher:

• From data to models: Systems biology methods and potential applications to toxicoinformatics (I. Androulakis) [presentation]

2/28/2008
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus

• Mutagenicity of air and water: mechanisms and biomarkers (David DeMarini, USEPA Environmental Carcinogenesis Division)

2/23-24/2008
MCBIOS 2008, Oklahoma City, OK

• Toxicogenomic studies reveal biosynthetic pathway of S-adenosylmethione as a possible hepatotoxic mechanism (M. Chen, L.K. Schnackenberg, L. Guo, R. Holland, R.D. Beger, Q. Shi, S. Isukapalli, P.G. Georgopoulos, W. Welsh, W. Tong) [abstract]

1/29-30/2008
ebCTC Science Days at EOHSI. An informal 2-day workshop with ebCTC researchers - "The path from ArrayTrack to ebTRack - Progress, Applications and Future Plans"

1/22/2008
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus

• Synthetic Biology for Bioinformatics (Max Garzon, University of Memphis)

2007

October-December 2007

12/20/2007
*Computational Toxicology Seminar, USEPA, Research Triangle Park, NC. Presentations by ebCTC reserchers:

• Optimal identification and analysis of bionetworks and biomolecules (Herschel Rabitz, Xiao-Jiang Feng) [presentation]
• Molecular modeling studies of interactions between xenobiotics and liver nuclear receptors (W.Welsh) [presentation]

12/6/2007
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus

• PBPK Modeling of Interactions and Risk Assessment of Chemical Mixtures (Kannan Krishnan, University of Montreal and visiting scholar at EOHSI)

11/4-9/2007
AIChE Annual Meeting, Salt Lake City, UT. Presentations by ebCTC reserchers:

• Toxicogenomics analysis following in utero exposure to di-butyl-phthalate (M.A. Ovacik, M.G. Ierapetritou, B. Sen, S. Euling, P.G. Georgopoulos, W. Welsh, K.W. Gaido, I.P. Androulakis) [abstract]
• A systematic toxicokinetic modeling framework for mixtures of toxic metals (A.F. Sasso, S.S. Isukapalli, P.G. Georgopoulos) [abstract]

11/1/2007
EOHSI/NIEHS Seminar Series, EOHSI Room C, Rutgers Busch Campus

• Genetical Genomics and Liver Toxicology: Making New Friends (Yvan Rusyn, Carolina Bioinformatics Center)

10/26/2007
Society of Environmental Toxicology and Chemistry (SETAC) Fall Workshop - Environmental Risk Assessment of Metals and Metalloids, Camden, NJ. Presentations by ebCTC reserchers:

• Integrating enviroinformatic and bioinformatic approaches for the systematic analysis of environmental human health risks from metals and metalloids (P.G. Georgopoulos, A.F. Sasso, S.S. Isukapalli) [abstract]
• Consistent physiologically based toxicokinetic modeling for mixtures of toxic metals and metalloids (A.F. Sasso, S.S. Isukapalli, P.G. Georgopoulos) [abstract]

10/25-26/2007
First International Conference on Toxicogenomics Integrated with Environmental Sciences (TIES), Raleigh, NC. Presentations by ebCTC reserchers:

• Pathway activity analysis for transcriptional profiling of in utero exposure to d-n-butyl phthalate (M.A. Ovacik, M.G. Ierapetritou, P.G. Georgopoulos, W. Welsh, S. Euling, B. Sen, K. Gaido, I.P. Androulakis) [abstract]
• ebTrack: an environmental bioinformatics system built upon ArrayTrack (M. Chen, S.S. Isukapalli, P.G. Georgopoulos, W.J. Welsh, W. Tong) [abstract]

10/14-18/2007
17th Annual Meeting of the International Society of Exposure Analysis, Durham, NC. Presentations by ebCTC reserchers:

• Modeling personal and ambient exposures to air toxics in Camden, New Jersey (S.W. Wang, X. Tang, Z. Fan, P.J. Lioy, P.G. Georgopoulos) [abstract]
• Systems toxicology: multiscale modeling of environmental impacts on bionetworks (W.J. Welsh, P.G. Georgopoulos) [abstract]
• Exposure biology for a systems approach in studying environmental health risks (P.G. Georgopoulos, S.S. Isukapalli, W. Tong, P.J. Lioy, W.J. Welsh) [abstract]
• Comparative evaluation of population exposure modeling approaches for reactive and non-reactive air pollutants (S.S. Isukapalli, J.E. Langstaff, D.J. Lucken, P.G. Georgopoulos) [abstract]
• Characterizing chemical exposure from biomonitoring data using the Exposure Related Dose Estimating Model (ERDEM) (C.C. Dary, P.G. Georgopoulos, D.A. Vallero, R. Tornero-Velez, M. Morgan, M. Okino, M. Dellarco, F. Power, J.N. Blancato) [abstract]
• Characterizing exposures to arsenic and co-occurring contaminants using the Modeling Environment for TOtal Risk studies (MENTOR) (P.G. Georgopoulos, S.W. Wang, A.F. Sasso, S.S. Isukapalli) [abstract]
• Comparative evaluation of screening and computational fluid dynamics (CFD) approaches for modeling inhalation exposures in indoor environments (S.K. Stamatelos, P.G. Georgopoulos) [abstract]
• Comparative evaluation of three statistical data mining techniques (CART, MARS, and Random Forest) and their applications in analyzing the NHANES VOC project data (S.W. Wang, Y. Yan, P.G. Georgopoulos) [abstract]
• Sensitivity analysis for studying impacts of aging on population toxicokinetics and toxicodynamics (A.F. Sasso, S.S. Isukapalli, E. Kenyon, P.G. Georgopoulos) [abstract]
• Physiologically based toxicokinetic modeling for mixtures of toxic metals (A.F. Sasso, S.S. Isukapalli, P.G. Georgopoulos) [abstract]
• Evaluation of methods for reconstructing exposures from biomarkers via PBTK models (S.S. Isukapalli, A.F. Sasso, M. Okino, P.G. Georgopoulos) [abstract]

10/9/2007
ebCTC Science Day: Researchers from the Princeton group lead presentations and discussions on Biological Network Dynamics in an informal session at EOHSI

July-September 2007

8/23/2007
ebCTC Science Day: Researchers from the Rutgers and UMDNJ groups lead discussions and presentations on Modeling of Chemical-Induced Carcinogenesis, at the Rutgers Department of Biomedical Engineering.

April-June 2007

5/21-23/2007
2007 International Science Forum on Computational Toxicology: Sponsored by USEPA at their main campus in Research Triangle Park, NC. ebCTC scientists presented several posters and also had a booth to present and discuss their work.

5/11/2007 and 5/18/2007
ebCTC Science Days: Researchers from the UMDNJ and Rutgers groups lead discussions and presentations on "virtual liver" technology in informal sessions at EOHSI.

4/26-27/2007
SYSTEMS TOXICOLOGY: Multiscale Modeling of Environmental Impacts on Bionetworks: A symposium presented by ebCTC and DIMACS, open to the research community

4/11/2007
*Computational Toxicology Seminar, USEPA, Research Triangle Park, NC. Presentation by ebCTC reserchers:

• Incorporating toxicogenomic data and approaches in risk assessment: Case study - phthalate esters (M. Ovacik, M.G. Ierapetritou, I.P. Androulakis, B. Sen, S. Euling, K. Gaido, P.G. Georgopoulos, W. Welsh) [presentation]

January-March 2007

3/14/2007
*Computational Toxicoloy Seminar: Optimization Tools for in silico Proteomics (P.A. DiMaggio Jr., C.A. Floudas)

2/28-3/1/2007
ebCTC Science Days: The Science and Technology for a "Virtual Liver": An informal 2-day workshop where ebCTC and USEPA visiting scientists exchanged information and ideas on concepts and computational tools for multiscale bionetwork modeling, from cell to organ

2006

October-December 2006

12/13/2006
*Computational Toxicology Tele-Seminar: Cheminformatics Tools for Toxicant Identification and Characterization (W. Welsh)

11/17/2006
ebCTC 2006 Overview Workshop at EOHSI: Visitors from USEPA met with and viewed presentations and posters by ebCTC scientists.

10/11/2006:
*Computational Toxicology Tele-Seminar: A closed-loop identification protocol (CLIP) for nonlinear biological networks (X-J. Feng, G. Li, H. Rabitz)

July-September 2006

9/29/2006
ArrayTrack Training at UMDNJ: Dr. Weida Tong, of USFDA-NCTR, provided hands-on training for ArrayTrack software at UMDNJ.

9/19/2006
ebCTC Science Day: New Methods and Tools of Computational Proteomics: The research team of Prof. Chris Floudas hosted a workshop on Computational Proteomics at Princeton University.

April-June 2006

6/14/2006
*Computational Toxicology Tele-Seminar: Computational Tools for the Source to Outcome Paradigm (P.G. Georgopoulos)

*Computational Toxicology Seminar Series
STAR Environmental Bioinformatic Centers Seminar Series at USEPA: In order to best interface the activities of the Environmental Bioinformatic Centers with the research being conducted within USEPA-ORD, an information program has been established. Each month, one of Centers presents an overview of the activities covered under one of their major projects. These sessions are open to all EPA staff who are interested in helping the Centers achieve their long-term objectives. While the number of interactions that can be developed are limited by available resources, these forums can facilitate the development of collaborative research projects. After the initial round of informational briefing, this program will evolve into a forum for presenting advances in environmental bioinformatics that will assist ORD in supporting the mission of the EPA of protecting human health and the environment.

Announcement of STAR Center Award
11/2/2005
News Release
EPA Announced an Award of $9 million to Establish Two Cutting-Edge Environmental Bioinformatics Research Centers