Recent and Upcoming Presentations (2008-2009)

Note: This listing begins with the most recent work. Presentations are provided with most abstracts; if you are interested in material that you don't see linked here, please contact Linda Everett with your request. Presentations available through this page are in Adobe Acrobat format; get the free Acrobat Reader here.

11/1-5/2009
2009 Annual Conference of ISES - Integrative Exposure Biology and Computational Toxicology for Risk Assessment Symposium, Minneapolis, MN

• Linking exposure dynamics with health effects through biological modeling: Case study with TCE exposure and oxidative stress (C.J. Brinkerhoff, P.G. Georgopoulos) [abstract]
• Integrative source-to-dose-to-effect modeling for interpreting biomonitoring data in an exposure context (P.G. Georgopoulos, S.S. Isukapalli) [abstract]
• Multiscale mechanistic models in exposure assessment: Case studies with virtual organs (S.S. Isukapalli) [abstract]
• Pathway modeling of microarray data of the rat testes after in utero DBP exposure (M. Ovacik, M.G. Ierapetritou, P. Georgopoulos, W. Welsh, S. Euling, B. Sen, K. Gaido, I.P. Androulakis) [abstract]
• Integrated computational models for supporting risk assessment: Case studies with chemical mixtures (A.F. Sasso, K. Krishnan, S.S. Isukapalli) [abstract]

9/2-6/2009
31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2009), Minneapolis, MN

• A unified multiscale field/network/agent based modeling framework for human and ecological health risk analysis (P.G. Georgopoulos, S. Isukapalli)

7/14/2009
Fourth Annual Interagency Workshop: Using Environmental Information to Prepare and Respond to Emergencies, New York, NY

• Improved assessment of risks from emergency events: Application of human exposure measurements (D.A. Vallero, S.S. Isukapalli, P.G. Georgopoulos, P.J. Lioy)

6/1-2/2009
NYC Continuity of Operations (NYC-COOP) Conference, New York, NY

• Integrating human exposures for improved assessment of risks from emergency events (S.S. Isukapalli, P.G. Georgopoulos, P.J. Lioy, D.A. Vallero)

5/20/2009
3rd Annual Systems Toxicology Symposium, Piscataway, NJ

Abstracts of the following presentations can be downloaded [608kb PDF].

• ebCTC research integration plan - Overview (P.G. Georgopoulos)
• Multiscale integration of toxicokinetic and toxicodynamic processes: From cells to tissues and organs (P.G. Georgopoulos)
• Pathway modeling of in utero DBP exposure in rat testes (M. Ovacik, M.G. Ierapetritou, P.G. Georgopoulos, W. Welsh, S. Euling, B. Sen, K. Gaido, I.P. Androulakis)
• Evaluation of computational platforms for simulating intracellular and intercellular interactions (C.T. Yung, D.P. Mukherjee, J.A. Alexander, S.S. Isukapalli, P.G. Georgopoulos)
• Progress and challenges in multiscale physiologically based toxicokinetic (PBTK) modeling of arsenic compounds (S.K. Stamatelos, A.F. Sasso, S.S. Isukapalli, P.G. Georgopoulos)
• Application of Bayesian analysis for studying toxicokinetics of mixtures: Application to co-occuring PCBs (A. Sasso, S.S. Isukapalli, P. G. Georgopoulos, K. Krishnan)
• Consideration of inter- and intra-individual variability in age/gender dependent dosimetry modeling of inhaled nanoparticles (P. Shade, P.G. Georgopoulos)
• A population exposure modeling system for co-occurring bioaerosols and air pollutants considering climatic change scenarios (C.I. Efstathiou, S.S. Isukapalli, L. Bielory, P.G. Georgopoulos)
• Progress in developing an infrastructure for virtual organs in a “whole body” framework: Virtual liver (S.S. Isukapalli, C.J Brinkerhoff, A. Sasso, M. Ierapetritou, I. Androulakis, C. Roth, P.G. Georgopoulos)
• Progress in developing an infrastructure for virtual organs in a “whole body” framework: Virtual skin (P.G. Georgopoulos, S.S. Isukapalli, A. Sasso, D. Gerecke)

5/14-15/2009
First ToxCast Data Analysis Summit (TDAS), USEPA Campus, Research Triangle Park, NC

• Data needs for progressing from hazard characterization to risk assessment: Analysis focusing on chemicals from the ToxCast database (C.J. Brinkerhoff, J.A. Alexander, C.T. Yung, S.S. Isukapalli, P.G. Georgopoulos) [abstract]
• Exposure reconstruction from biomonitoring data using screening level approaches: application to chemicals in the ToxCast database (C.J. Brinkerhoff, J.A. Alexander, A.F. Sasso, S.S. Isukapalli, P.G. Georgopoulos) [abstract]
• Progress in the development of ebTrack, an open environmental bioinformatics system: design considerations related to the support of consistent multi-attribute ToxCast data analyses (P.G. Georgopoulos, M. Chen, S.S. Isukapalli, W. Welsh, W. Tong) [abstract]
• Relating toxicity profiles to molecular structures: A preliminary analysis of the transcription factor assays data from Attagene Inc. (D. Chekmarev, V. Kholodovych, N. Ai, P.G. Georgopoulos, W. Tong, W.J. Welsh) [abstract]

5/11-13/2009
Toxicity Pathway Based Risk Assessment: Preparing for Paradigm Change. The National Academy of Sciences, Washington, DC

• Application of an integrated bioinformatics system for pathway-based analysis of toxicity data (S. Isukapalli, D. Gerecke, Y.C.  Chang, M. Chen, I. Androulakis, W. Welsh, W. Tong, P.G. Georgopoulos) [abstract]
• Toxicity pathway modeling of chemically induced oxidative stress: A case study with trichloroethylene (C.J. Brinkerhoff, S.S. Isukapalli, P.G. Georgopoulos) [abstract]

5/5/2009
Exposure Science Community of Practice Teleconference. USEPA Campus, Research Triangle Park, NC

• Connecting environment, biology, and behavior for human exposure and risk assessment: Integrative modeling approaches (P.G. Georgopoulos) [presentation]

4/21-23/2009
v-Tissue 2009: The EU-US Workshop on Virtual Tissues. USEPA, Research Triangle Park, NC

• Frameworks for linking exposure, dosimetry and toxicity (P.G. Georgopoulos)

3/18/2009
Cancer Institute of NJ Genetic Epidemiology and Population Biology Research Program Meeting. Institute for Advanced Studies, Princeton, NJ

• Environmental carcinogens and exposure biology challenges (P.G. Georgopoulos)

3/15-18/2009
48th Annual Meeting of the Society of Toxicology (SOT). Baltimore, MD

• A novel algorithm for computing interaction-based hazard index for the health risk assessment of chemical mixtures (S.S. Isukapalli, A.F. Sasso, P.G. Georgopoulos, K. Krishnan) [abstract]
• An integrated species comparison analysis based on biological pathways (M. Ovacik, S. Euling, B. Sen, P.G. Georgopoulos, M.G. Ierapetritou, I.P. Androulakis) [abstract]
• Temporal pathway activity analysis of transcriptional profiling of in utero exposure to d-n-butyl phthalate (M. Ovacik, M.G. Ierapetritou, P.G. Georgopoulos, W. Welsh, S. Euling, B. Sen, K. Gaido, I.P. Androulakis) [abstract]

3/13-17/2009
2009 Annual Meeting of the American Academy of Allergy, Asthma, and Immunology. Washington, DC

• A modeling system for supporting population exposure assessment to bioaerosols and other air pollutants (S.S. Isukapalli, C. Efstathiou, L.J. Bielory, P.G. Georgopoulos) [abstract]
• A novel modeling system for estimating pollen emissions: Application to Northeast US (C. Efstathiou, L.J. Bielory, and P.G. Georgopoulos) [abstract]

1/18-21/2009
2nd International Conference on Biomolecular Engineering. Santa Barbara, CA

• Multiscale physiologically based toxicokinetic (PBTK) modeling: A case study for arsenic compounds (S.K. Stamatelos, C.J. Brinkerhoff, A.F. Sasso, S.S. Isukapalli, P.G. Georgopoulos) [abstract]

12/7-10/2008
Society of Risk Analysis (SRA) 2008 Annual Meeting. Boston, MA

• A novel interaction-based algorithm for predicting biological doses during chronic exposures to chemical mixtures (S.S. Isukapalli, A.F. Sasso, P.G. Georgopoulos, K. Krishnan) [abstract]

12/5/2008
NJ Universities Homeland Security Research Consortium. Princeton, NJ

• Computational modeling for supporting emergency event response: population exposures to anthrax (S.S. Isukapalli, P.J. Lioy, P.G. Georgopoulos) [abstract]
• Bioinformatics techniques for disease detection and finding medical countermeasures: Case study with sulfur mustard (D.R. Gerecke, M. Chen, S.S. Isukapalli, M.K. Gordon, Y.C. Chang. W. Tong, I.P. Androulakis, P.G. Georgopoulos) [abstract]
• Computational modeling of indoor dynamics of chemical warfare agents: Case study with indoor releases of sarin (P.G. Georgopoulos, S.K. Stamatelos, P. George, S.S. Isukapalli) [abstract]

11/19/2008
Meeting of the Tri-State Chapter of the International Society of Exposure Science (ISES). Piscataway, NJ

• Modeling exposures to environmental and biological agents (S. Isukapalli, P.G. Georgopoulos)

11/16-21/2008
2008 AIChE Annual Meeting. Philadelphia, PA

• Physiologically-based inhalation dosimetry modeling for nanoparticles: Considerations of activity, age, and gender (P. Shade, P.G. Georgopoulos) [abstract]
• In silico modeling of uptake and metabolism of arsenicals in hepatocytes with implications for hepatotoxicity (S.K. Stamatelos, C.J. Brinkerhoff, A.F. Sasso, S.S. Isukapalli, P.G. Georgopoulos) [abstract]
• Indirect response model of arsenic exposure on gene expression (M.A. Ovacik, M.G. Ierapetritou, P.G. Georgopoulos, W.J. Welsh, I.P. Androulakis) [abstract]

10/12-16/2008
ISEE/ISEA 2008 Concerence. Pasadena, CA

• Model estimates of arsenic exposure and dose and evaluation with 2003 NHANES data (J. Xue, V. Zartarian, S.W. Wang, and P.G. Georgopoulos) [abstract]

8/24-29/2008
European Aerosol Conference (EAC) 2008. Thessaloniki, Greece

• Evaluation of aerosol and ozone simulations over Athens using in situ sensors combined with health indicators (A. Poupkou, I. Ziomas, A. Papayannis, P. Georgopoulos, C. Efstathiou, K. Eleftheriadis, K. Markakis, N. Sifakis, C. Housiadas, P. Nicolopoulou-Stamati, G. Avdikos, M. Lazaridis, T. Giannaros)

6/29-7/3/2008
Protection and Restoration of the Environment IX (PRE9) Conference. Kefalonia, Greece

• Mechanistic studies of environmental causes of human disease: a bionetwork dynamics modeling approach (P.G. Georgopoulos) [abstract]
• Modeling the impact of airport activities on local scale air quality (C. Efstathiou, A. Vemuri, S-W. Wang, P.G. Georgopoulos) [abstract]
• Short and long-term environmental impacts of wildfires (post-conference workshop, July 4) (P.G. Georgopoulos)

4/30-5/1/2008
The 2nd Annual Systems Toxicology Symposium: Multiscale Modeling, from Molecules to Organisms. Piscataway, NJ

Abstracts of the following presentations can be downloaded [570kb PDF].

• A multiscale framework for environmental systems toxicology (P.G. Georgopoulos)
• The indirect response model of arsenic exposure on gene expression  
  (M.A. Ovacik, M.G. Ierapetritou, P.G. Georgopoulos, W.J. Welsh, I.P. Androulakis)
• Gene expression studies of mouse skin response to sulfur mustard exposure for evaluating efficacy of inhibitors (D.R. Gerecke, M. Chen, S. Isukapalli, Y-C. Chang, W. Tong, I.P. Androulakis, P.G. Georgopoulos)
• Physiologically based inhalation dosimetry modeling for nanoparticles: Considerations of activity, age and gender (P. Shade, P.G. Georgopoulos)
• Efficient physiologically-based algorithms for estimating internal doses occuring due to chronic exposures of organics (S.S. Isukapalli, A.F. Sasso, P.G. Georgopoulos, K. Krishnan)
• User oriented implementation of a generalized Physiologically-Based Toxicokinetic (PBTK) modeling framework for mixtures (A.F. Sasso, P.G. Georgopoulos)
• Pharmacokinetic model of uptake and metabolism of arsenicals in hepatocytes with implications for reactive oxygen species generation and hepatocarcinogenesis (C.J. Brinkerhoff, S. Stamatelos, S.S. Isukapalli, P.G. Georgopoulos)
• Progress in developing infrastructure for a virtual liver I: Essential concepts and modules (P.G. Georgopoulos, W.J. Welsh, S.S. Isukapalli, M. Ierapetritou, I. Androulakis, C.M. Roth, W. Tong)
• Progress in developing infrastructure for a virtual liver II: Multiscale studies of hepatotoxicants for elucidating potential biomarkers and important pathways related to hepatotoxicity (M. Chen, L. Schnackenberg, L. Guo, R. Holland, R. Beger, Q. Shi, S.S. Isukapalli, P.G. Georgopoulos, W.J. Welsh, W. Tong)
• Progress in developing infrastructure for a virtual liver V: PBTK/TD models with zonal and distributed parameters for metabolism of environmental toxins (S.S. Isukapalli, C.J. Brinkerhoff, A.F. Sasso, P.G. Georgopoulos)

4/15/2008
USEPA Region 2 Seminar - Evaluating Fish Consumption Guidelines: A Qualitative and Quantitative Approach for High Risk Ethnic Groups. New York, NY

• Modeling dietary human exposures to mercury and methylmercury using a probabilistic source-to-dose approach (S.W. Wang, A. Sasso, Y.C. Yang, P.G. Georgopoulos J. Xue, T. McCurdy, H. Ozkaynak) [presentation]

4/14-17/2008
International Conference on Health Sciences Simulation. Ottawa, Canada

• A physiologically-based algorithm for predicting internal dose of inhaled toluene: Applications for high dose to low dose and rodent to human extrapolations (S.S. Isukapalli, K. Price, P.G. Georgopoulos, K. Krishnan) [abstract]

3/16-20/2008
47th Annual Meeting of the Society of Toxicology (SOT). Seattle, WA

• Toxicogenomic studies reveal the transsulfuration pathway as a possible mechanism for liver toxicity (M. Chen, L.K. Schnackenberg, L Guo, R. Holland, R.D. Beger, S. Isukapalli P.G. Georgopoulos, W.J. Welsh, W. Tong) [presentation]

2/13-24/2008
MidSouth Computational Biology and Bioinformatics Society - MCBIOS 2008. Oklahoma City, OK

• Toxicogenomic studies reveal biosynthetic pathway of S-adenosylmethione as a possible hepatotoxic mechanism (M. Chen, L.K. Schnackenberg, L. Guo, R. Holland, R.D. Beger, Q. Shi, S. Isukapalli, P.G. Georgopoulos, W. Welsh, W. Tong) [abstract]

Other Presentations: 2008-2009 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 & earlier